The Peptide Compound Index
Every research compound in our library — 60 peptides organised by category, each with an evidence tier from S (FDA-approved) to D (preclinical only). Every entry links to a full page with mechanism, protocols, synergies, biomarkers, and primary-source citations from PubMed and clinical-trial registries.
Tier S FDA-approved with overwhelming human data
Tier A Strong human RCT data
Tier B Promising, some human data + strong preclinical
Tier C Early or mixed, limited human trials
Tier D Preclinical or animal data only
Tissue Repair & Recovery
Peptides that accelerate wound healing, tendon and ligament repair, gut mucosal recovery, and nerve regeneration.
GHK-Cu
Copper Tripeptide Glycine-Histidine-Lysine
Age-reversing copper tripeptide that activates 4,000+ genes — collagen synthesis, antioxidant defence, and neuroregeneration.
Teriparatide
PTH(1-34) / Forteo — Bone Anabolic Peptide
FDA-approved PTH fragment — the only anabolic bone therapy (builds bone, doesn't just stop breakdown). Reduces fracture risk 65–70%.
ACE-031
ACVR2B-Fc — Activin Receptor Type IIB Fusion Protein
Myostatin pathway inhibitor via decoy receptor — Phase II muscle mass gains halted due to vascular side effects.
BPC-157
Body Protection Compound-157
The tissue-healing workhorse — accelerates repair of tendons, ligaments, gut lining, and nerves via VEGF-driven angiogenesis.
Follistatin
FST — Activin Antagonist and Myostatin Inhibitor
Endogenous myostatin inhibitor — dramatic muscle growth in animal models; human gene therapy trials underway.
TB-500
Thymosin Beta-4 Fragment Tβ4(17-23)
Systemic tissue repair and anti-fibrotic — mobilises repair cells body-wide via actin sequestration and PI3K/Akt signalling.
IGF-1 DES
Des(1-3)IGF-1 — N-Terminal Truncated IGF-1
Truncated IGF-1 analogue — 10× higher potency than IGF-1 LR3 with extremely local effects and shorter half-life.
MGF
Mechano Growth Factor — IGF-1Ec Splice Variant
Muscle-specific IGF-1 splice variant — activated by mechanical loading, drives satellite cell activation and muscle repair.
Growth Hormone Secretagogues
Compounds that stimulate endogenous growth-hormone release via the pituitary — used for recovery, sleep, and body composition research.
Sermorelin
GHRH(1-29) — FDA-Approved GH Secretagogue
The most clinically validated GH secretagogue — FDA-approved, longest safety record, physiological pulsatile GH release.
CJC-1295 (no DAC)
Modified GRF 1-29 — Short-Acting GHRH Analogue
The gold-standard GHRH analogue — amplifies pituitary GH pulses physiologically. Best combined with Ipamorelin.
CJC-1295 DAC
Long-Acting GHRH with Drug Affinity Complex
Once-weekly GHRH — albumin-binding DAC extends half-life to 6–8 days for sustained GH and IGF-1 elevation.
Hexarelin
Examorelin — Most Potent GHRP
The most potent GHRP in terms of GH peak — also has direct cardiac protective effects via CD36 receptor, independent of GH.
MK-677
Ibutamoren — Oral GH Secretagogue
Orally active non-peptide GH secretagogue — once-daily pill elevates GH and IGF-1 with Phase II human RCT data.
GHRP-2
Growth Hormone Releasing Peptide-2 — Pralmorelin
Potent GH secretagogue — stronger GH release than Ipamorelin but with cortisol and prolactin co-stimulation.
GHRP-6
Growth Hormone Releasing Peptide-6 — First GHRP
The original GHRP — powerful GH release with significant appetite stimulation via ghrelin pathway activation.
IGF-1 LR3
Long R3 Insulin-like Growth Factor 1
Direct anabolic signalling via IGF-1 receptor — enhanced potency with 20–30× longer half-life than native IGF-1.
Ipamorelin
Selective Growth Hormone Releasing Peptide (GHRP)
The cleanest GHRP — selective pituitary GH stimulation with zero cortisol or prolactin side effects.
HGH 191aa
Recombinant Human Growth Hormone (Somatropin) — 191 Amino Acid Sequence
The gold standard — recombinant somatropin, identical to endogenous HGH. S-tier by FDA approval and decades of clinical data.
Cognitive & Neurological
Peptides with documented CNS effects — memory, focus, neuroprotection, and recovery from neurological injury.
Oxytocin
Oxytocin — The "Bonding" Neuropeptide
FDA-approved neuropeptide — drives bonding, trust, and social cognition. Intranasal research shows real anxiolytic and pro-social effects.
Cerebrolysin
FPF-1070 — Brain-Derived Peptide Mixture
European-approved neurotrophic peptide mixture — enhances BDNF/NGF, approved for Alzheimer's and stroke in 50+ countries.
DSIP
Delta Sleep-Inducing Peptide — Nonapeptide
Endogenous sleep peptide — reduces cortisol, promotes restorative delta-wave sleep, and modulates stress responses.
Dihexa
N-hexanoic-Tyr-Ile-(6) aminohexanoic amide — HGF Potentiator
The most potent synaptogenic compound discovered — 7 orders of magnitude more potent than BDNF in animal models.
Orexin-A
Hypocretin-1 — Wakefulness-Promoting Neuropeptide
Master wakefulness peptide — deficiency causes narcolepsy. Intranasal orexin-A restores alertness and cognitive performance.
P21
P21 — CNTF-Derived Neuroprotective Peptide
CNTF-derived neuroprotective peptide — promotes neurogenesis and adult neural stem cell proliferation.
PE-22-28
Spadin Analogue — Antidepressant Peptide
Spadin-derived TREK-1 channel blocker — fast-acting antidepressant effects in animal models, unique non-monoaminergic mechanism.
Selank
TP-7 — Heptapeptide Anxiolytic Nootropic (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
Russian anxiolytic peptide — reduces anxiety without sedation or dependence, modulates GABA/serotonin and enhances learning.
Semax
ACTH(4-7) Pro-Gly-Pro — Synthetic Neuropeptide
Russian nootropic derived from ACTH — potent BDNF upregulation, enhanced focus, and neuroprotection. Approved in Russia/Ukraine.
Longevity & Anti-Ageing
Compounds targeting hallmarks of ageing — telomere length, senescent-cell clearance, mitochondrial biogenesis, and DNA repair.
Carnosine
Beta-Alanine-L-Histidine — Endogenous Dipeptide
Endogenous dipeptide concentrated in muscle and brain — anti-glycation, antioxidant, pH buffering, and anti-ageing activity.
Epitalon
Epithalon — Tetrapeptide Ala-Glu-Asp-Gly
The longevity tetrapeptide — activates telomerase, extends telomere length, and modulates pineal melatonin output.
FOXO4-DRI
FOXO4-p53 Interaction Disruptor — Senolytic Peptide
The most targeted senolytic discovered — kills senescent cells by disrupting p53 survival signalling. Dramatic results in mouse ageing.
Pinealon
Ala-Glu-Asp-Gly — Pineal Gland-Derived Tetrapeptide
Pineal gland peptide bioregulator — epigenetic gene expression, circadian rhythm support, and neuroprotection.
Metabolic & Weight Management
GLP-1/GIP/glucagon co-agonists, appetite regulators, and body-composition compounds studied in metabolic disease research.
Liraglutide
Victoza / Saxenda — First-Generation Daily GLP-1 Agonist
FDA-approved daily GLP-1 agonist — predecessor to semaglutide with strong RCT evidence for weight loss and T2DM.
Retatrutide
LY3437943 — GIP/GLP-1/Glucagon Triple Agonist
The most potent incretin triple agonist in Phase III — GIP + GLP-1 + Glucagon receptor activation for superior weight loss and metabolic benefit.
Tesamorelin
Stabilised GHRH Analogue — FDA-Approved (Egrifta)
FDA-approved for visceral fat reduction — the most evidence-backed GHRH analogue for metabolic and body composition research.
Glucagon
Glucagon — Counter-Regulatory Hormone
FDA-approved life-saving peptide for severe hypoglycaemia — now foundational component of GLP-1/GIP/glucagon triple agonists.
AOD-9604
Anti-Obesity Drug 9604 — C-Terminal GH Fragment
GH-derived fat-targeting fragment — specifically activates lipolysis in adipose tissue without GH's growth-promoting effects.
5-Amino-1MQ
5-Amino-1-Methylquinolinium — NNMT Inhibitor
Small molecule NNMT inhibitor — activates cellular NAD+ production and reverses adipocyte hypertrophy in animal models.
Adropin
ENHO Peptide — Energy Homeostasis Hormone
Newly discovered metabolic hormone — regulates fuel selection, endothelial function, and cognitive performance.
BRP
Beta-Rug Peptide (BRP) — Ghrelin O-Acyltransferase Inhibitor
Novel appetite-suppressing peptide targeting ghrelin acylation — very early preclinical stage.
Irisin
FNDC5 Cleavage Product — Exercise Hormone
Exercise-induced myokine — drives WAT-to-BAT conversion, bone health, and cognitive enhancement via exercise mimicry.
Insulin
Human Insulin — Anabolic Master Hormone
The body's primary anabolic hormone — FDA-approved, essential for glucose metabolism and protein synthesis.
Semaglutide
Ozempic / Wegovy — GLP-1 Receptor Agonist
FDA-approved GLP-1 agonist — the most effective pharmacological weight loss agent in history (15–20% body weight reduction).
Tirzepatide
Mounjaro / Zepbound — GLP-1 + GIP Dual Agonist
Dual GLP-1/GIP agonist with superior weight loss to semaglutide — 22.5% body weight reduction in SURMOUNT-1.
Mitochondrial Function
Peptides that act at the mitochondrial level — cardiolipin protection, ATP production, and redox signalling.
NAD+
Nicotinamide Adenine Dinucleotide — IV / SubQ / Nasal Administration
The cellular energy currency and sirtuin activator — declines with age, supplementation supports mitochondrial function, DNA repair, and longevity pathways.
SS-31 / Elamipretide
Szeto-Schiller Peptide 31 — Mitochondria-Targeted Cardioprotective Peptide
Cardiolipin stabiliser targeting the inner mitochondrial membrane — the most advanced mitochondrial peptide in clinical research.
Humanin
Mitochondria-Encoded Cytoprotective Peptide
Encoded in mitochondrial DNA — cytoprotective peptide declining with age, neuroprotective and anti-apoptotic in preclinical models.
MOTS-c
Mitochondrial Open Reading Frame of the 12S rRNA-c Peptide
Mitochondrial-encoded exercise mimetic — activates AMPK, improves insulin sensitivity, and drives mitochondrial biogenesis.
Immune & Inflammation
Immunomodulators — thymic peptides, cytokine modulators, and inflammation-regulating compounds.
Thymosin Alpha-1 / TA-1
Thymalfasin — Thymic Immunomodulatory Peptide
The gold standard immune modulator — FDA-approved equivalent (Zadaxin) with strong RCT data in viral infections, cancer, and immune deficiency.
ARA-290
Cibinetide — Erythropoietin-Derived Tissue Protection Peptide
EPO-derived neuroprotective and anti-inflammatory peptide — tissue protection without erythropoietic effects.
KPV
Lys-Pro-Val — Alpha-MSH C-Terminal Tripeptide
Endogenous anti-inflammatory tripeptide derived from alpha-MSH — potent gut inflammation modulator with topical and oral research.
Thymalin
Thymus-Derived Peptide Complex — Polypeptide Bioregulator
Thymus-derived immunomodulatory peptide mixture — used in Russian longevity medicine alongside Epitalon for immune restoration.
VIP
Vasoactive Intestinal Peptide — 28-Amino Acid Neuropeptide
Potent immunomodulator and vasodilator with documented anti-inflammatory and pulmonary protective effects.
LL-37
Human Cathelicidin Antimicrobial Peptide — hCAP18 Active Fragment
The body's native antimicrobial peptide — kills bacteria, viruses, fungi, and biofilms while modulating immune signalling.
Hormonal Modulation
Compounds that modulate endocrine axes — melanocortin, oxytocin, kisspeptin, and related peptide hormones.
Gonadorelin
GnRH — Gonadotropin-Releasing Hormone
Endogenous GnRH peptide — FDA-approved for hypogonadism diagnosis, used clinically to preserve testicular function during TRT.
Leuprolide
Lupron — GnRH Agonist for Hormonal Suppression
FDA-approved GnRH agonist — initial LH/FSH stimulation followed by HPG axis suppression via receptor downregulation.
hCG
Human Chorionic Gonadotropin — LH Analogue
Endogenous LH analogue — FDA-approved for fertility. Used clinically to maintain testicular function and spermatogenesis during TRT.
Kisspeptin
Full-Length Kisspeptin-54 — KISS1 Protein
The upstream master regulator of reproduction — full-length form studied for HPG axis restoration and IVF enhancement.
Kisspeptin-10
Kisspeptin-10 — Metastin Fragment (112–121)
Master regulator of GnRH pulsatility — drives LH/FSH release and restores hormonal axis in hypogonadotrophic hypogonadism.
Sexual Health
Melanocortin agonists studied for sexual response independent of vascular pathway.
PT-141
Bremelanotide — Melanocortin Receptor Agonist
FDA-approved melanocortin agonist for hypoactive sexual desire disorder — acts centrally on the brain, not the vascular system.
Melanotan II
MT-II — Non-Selective Melanocortin Agonist
Non-selective melanocortin agonist — potent tanning and sexual effects, but significant safety concerns vs. PT-141.